Three-Game Series vs. St. Louis Cardinals
White Sox win series 2-1
Lynn 
Kim
Monday, May 24, 2021 at 7:10 pm CDT
Guaranteed Rate Field
Lance Lynn, RHP vs.
Cardinals / Kwang Hyun Kim, LHP
W, 5-1, 27-19 (.587), W1 | WP: Lance Lynn (5-1, 1.32) | Game 46
Watch game highlights from mlb.com:
Giolito 
Flaherty
Tuesday, May 25, 2021 at 7:10 pm CDT
Guaranteed Rate Field
Lucas Giolito, RHP vs.
Cardinals / Jack Flaherty, RHP
W, 8-2, 28-19 (.596), W2 | WP: Lucas Giolito (4-4, 4.04) | S: Liam Hendriks (10) | Game 47
Watch game highlights from mlb.com:
Rodón 
Grant
Wednesday, May 26, 2021 at 2:10 pm CDT
Guaranteed Rate Field
Carlos Rodón, LHP vs.
Cardinals / John Grant, RHP
L, 4-0, 28-20 (.583), L1 | LP: Carlos Rodón (5-2, 1.29) | Game 48
Watch game highlights from mlb.com:
Adam Engel to Rehab
May 25—Outfielder Adam Engel has been assigned to the Charlotte Knights for rehab. Engel has been on the injured list since March 21, having injured the right hamstring in spring training.
Four-Game Series vs. Baltimore Orioles
White Sox sweep series 4-0
Cease 
Zimmermann
Thursday, May 27, 2021 at 7:10 pm CDT
Guaranteed Rate Field
Dylan Cease, RHP vs.
Orioles / Bruce Zimmermann, LHP
W, 5-1, 29-20 (.592), W1 | WP: Dylan Cease (3-1, 2.98) | Game 49
Watch game highlights from mlb.com:
Lynn 
Means
Friday, May 28, 2021 at 7:10 pm CDT
Guaranteed Rate Field – Rained Out
Lance Lynn, RHP vs.
Orioles / John Means, LHP
Postponed due to rain. Rescheduled for tomorrow (May 29) as the second game of a straight doubleheader. The second game will begin 30-45 minutes after the conclusion of the regularly scheduled game which begins at 1:10 pm CDT.
Keuchel 
Harvey
Saturday, May 29, 2021 at 1:10 pm CDT
Guaranteed Rate Field – 7-inning Game
Dallas Keuchel, LHP vs.
Orioles / Matt Harvey, RHP
W, 7-4, 30-20 (.600), W2 | WP: Dallas Keuchel (4-1, 4.53) | Liam Hendriks (11) | Game 50
Watch game highlights from mlb.com:
Lynn Means
Saturday, May 29, 2021 at 4:35 pm CDT
Guaranteed Rate Field – Makeup of May 28 (7-innings)
Lance Lynn, RHP vs.
Orioles / John Means, LHP
W, 3-1, 31-20 (.609), W3 | WP: Lance Lynn (6-1, 1.20) | S: Liam Hendriks (12) | Game 51
Watch game highlights from mlb.com:
Giolito 
Akin
Sunday, May 30, 2021 at 1:10 pm CDT
Guaranteed Rate Field
Lucas Giolito, RHP vs.
Orioles / Keegan Akin, LHP
W, 3-1, 32-20 (.615), W4 | WP: Lucas Giolito (5-4, 3.73) | Liam Hendriks (13) | Game 52
Watch game highlights from mlb.com: