For the first time, the 2021 MLB Draft is part of All-Star Week, at Bellco Theatre in Denver.
Schedule
• Round 1 – Sunday, July 11 at 6:00 pm CDT on ESPN
• Rounds 2-10 – Monday, July 12 at 12:00 pm CDT on MLB.com
• Rounds 11-20 – Tuesday, July 13 at 11:00 am CDT on MLB.com
Analysis
For an in-depth look at every White Sox draft pick, monitor the coverage by Sox on 35th.
Round 1 – Colson Montgomery
2021 White Sox Picks
| Round | Pick | Position | School / Commit |
| 1 (22) | Colson Montgomery (19) | SS | Southridge HS (IN) / Indiana |
| 2 (57) | Wes Kath (18) | 3B/SS | Desert Mountain HS (AZ) / Arizona State |
| 3 (75) | Sean Burke (21) | RHP | Maryland, 4-yr. Sr. |
| 4 (124) | Brooks Gosswein (22) | LHP | Bradley, 4-yr. Sr. |
| 5 (155) | Tanner McDougal (18) | RHP | Silverado HS (NV) / Oregon |
| 6 (185) | Taylor Broadway (24) | RHP | Mississippi, 4-yr. 5S |
| 7 (215) | Theo Denlinger (25) | RHP | Bradley, 4-yr. 5S |
| 8 (245) | Fraser Ellard (23) | LHP | Liberty, 4-yr. 5S |
| 9 (275) | Gil Luna Jr. (21) | LHP | Arizona, 4-yr. Sr. |
| 10 (305) | Tommy Sommer (22) | LHP | Indiana, 4-yr. Sr. |
| 11 (335) | Christian Edwards (22) | RHP | Jacksonville State, 4-yr. Sr. |
| 12 (365) | Johnny Ray (22) | RHP | TCU, 4-yr. Sr. |
| 13 (395) | Colby Smelley (21) | C | Shelton State Community College (AL), JC J3 |
| 14 (425) | Noah Owen (20) | RHP | Golden West College (CA), JC J3 |
| 15 (455) | Cameron Butler (18) | OF | Big Valley Christian HS (CA) |
| 16 (485) | Terrell Tatum (21) | OF | NC State, 4-yr. Jr. |
| 17 (515) | Jayson Gonzalez (22) | 3B | Vanderbilt, 4-yr. Sr. |
| 18 (545) | Adam Hackenberg (21) | C | Clemson, 4-yr. Jr. |
| 19 (575) | Shawn Goosenberg (21) | SS | Northwestern, 4-yr. Jr. |
| 20 (605) | Haylen Green (23) | LHP | TCU, 4-yr. 5S |